7521 NE 222nd Street, Melrose, FL 32666
Local realty services provided by:Tomlin St Cyr Real Estate Services ERA Powered
Listed by: lindsey johnson
Office: keller williams gainesville realty partners
MLS#:GC541231
Source:MFRMLS
Price summary
- Price:$595,000
- Price per sq. ft.:$444.69
About this home
Some homes check the boxes. Others make you feel something the moment you arrive.
Originally built in 1956 as two neighboring fish camps, this one-of-a-kind waterfront home has been thoughtfully transformed into a warm, inviting retreat while preserving the character that makes it so special. Sitting on 0.7 acres with more than 100 feet of shoreline on Big Lake Santa Fe, this is the kind of property where mornings begin with breathtaking sunrises over the water and evenings end on the porch after a day on the lake.
With nearly 500 acres of surface water and depths reaching up to 26 feet, Big Lake Santa Fe is one of North Central Florida's most treasured lakes, offering year-round boating, skiing, fishing, paddleboarding, and endless days on the water. The property even includes its own natural lagoon with a small boat ramp, and the dock was extensively improved in 2023 with new pilings where needed, an extended platform, and a 5,000-pound Dolphin boat lift ready for your ski boat or pontoon.
Inside, every room reflects the care and creativity of the current owners. The remodeled kitchen features custom cabinetry, updated countertops, appliances, and fixtures, while beautiful luxury vinyl plank flooring flows throughout the living spaces and new tile enhances both bathrooms. Thoughtful details—from the wood accents and designer lighting to the carefully chosen finishes—create a home that feels both timeless and effortlessly welcoming.
One of the highlights is the incredible 31-foot screened porch, added in 2020. It's the perfect place to sip your morning coffee as the sun rises over the lake, watch afternoon storms roll across the water, or gather with friends long after the sun goes down.
The home offers 2 bedrooms, 2 baths, plus a versatile bonus room that could easily serve as a third bedroom, office, bunk room, or creative studio. A unique guest bath connects directly to the utility room and exterior door, making cleanup after swimming, fishing, or working outdoors incredibly convenient.
Outside, the property continues to impress. Mature cypress trees frame the lake without stealing the view, while a fully fenced yard with an electric gate offers privacy and peace of mind. A powered workshop and separate storage shed provide plenty of space for tools, hobbies, lake toys, and equipment.
Nearly every major component has been improved, including a metal roof, updated windows and doors, remodeled kitchen and bathrooms, luxury flooring, exterior paint, new water heater (2026), gutters with guards, finished laundry room, sump pump (2021), septic service, and much more—allowing the next owner to simply move in and start enjoying lake life.
Whether you're searching for a full-time residence, a weekend escape, or a vacation rental with exceptional appeal, this property offers something that's becoming increasingly difficult to find: authentic character, modern updates, and a front-row seat to one of North Central Florida's most beautiful lakes.
Some houses are just places to live. This one is where memories are made. Need more room for family or guests? The beautifully built 2021 custom home directly across the street is also available. Purchase both together at a discounted package price to create your own private Big Lake Santa Fe retreat. (GC541232)...
Contact an agent
Home facts
- Year built:1956
- Subdivision & Development:N/A
- Listing ID #:GC541231
- Added:50 day(s) ago
- Updated:August 17, 2026 at 11:13 AM
Rooms and interior
- Bedrooms:2
- Total bathrooms:2
- Full bathrooms:2
- Flooring:Ceramic Tile, Luxury Vinyl
- Dining Description:Eat In Kitchen
- Kitchen Description:Dishwasher, Eat-in Kitchen, Range, Range Hood, Refrigerator
- Bedroom Description:High Ceilings, Primary Bedroom Main Floor, Split Bedroom, Walk-In Closet(s)
- Living area:1,042 sq. ft.
Heating and cooling
- Cooling:Mini-Split Unit(s)
- Heating:Central
Structure and exterior
- Roof:Metal
- Year built:1956
- Building area:1,042 sq. ft.
- Lot area:0.7 Acres
- Construction Materials:Concrete
- Exterior Features:Rain Gutters, Rear Porch, Screened
- Foundation Description:Slab
- Levels:1 Story
Schools
- High school:Hawthorne Middle/High School-AL
- Middle school:Hawthorne Middle/High School-AL
- Elementary school:Chester Shell Elementary School-AL
Utilities
- Water:Well
- Sewer:Septic Tank
Finances and disclosures
- Price:$595,000
- Price per sq. ft.:$444.69
- Tax amount:$4,840 (2025)
Features and amenities
- Appliances:Dishwasher, Dryer, Range, Range Hood, Refrigerator, Washer
- Laundry features:Dryer, Inside, Washer
- Amenities:Ceiling Fans(s), Eat-in Kitchen, High Ceilings, Primary Bedroom Main Floor, Split Bedroom, Vaulted Ceiling(s), Walk-In Closet(s)
- Pool features:Public Pool
New listings near 7521 NE 222nd Street
- New
$169,900Active2 beds 1 baths900 sq. ft.125 Lemon Street, Melrose, FL 32666
MLS# 2159787Listed by: FLORIDA HOMES REALTY & MTG LLC - New
$60,000Active2 Acres115 Orange Tree Court, MELROSE, FL 32666
MLS# TB8538070Listed by: KELLER WILLIAMS TAMPA PROPERTIES - New
$24,900Active0.22 AcresCounty Road 315, MELROSE, FL 32666
MLS# GC542622Listed by: PEPINE REALTY - New
$775,000Active3 beds 2 baths2,034 sq. ft.135 Pearsall Circle, Melrose, FL 32666
MLS# 2159365Listed by: FLORIDA HOMES REALTY & MTG LLC - New
$585,000Active3 beds 2 baths2,995 sq. ft.7932 Breezy Point W Road, Melrose, FL 32666
MLS# 2158864Listed by: DOGWOOD REALTY
$90,000Active4.04 AcresCounty Road 315c, MELROSE, FL 32666
MLS# GC542521Listed by: PEPINE REALTY
$260,000Active3 beds 2 baths2,330 sq. ft.119 Ramsey Dr, Other, FL 32666
MLS# A12065752Listed by: EQUITABLE COMPANY REALTORS
$79,900Active0.67 Acres404 Grove Street, Melrose, FL 32666
MLS# 2158521Listed by: FLORIDA HOMES REALTY & MTG LLC
$30,000Active0.61 Acres118 Ramsey Drive, Melrose, FL 32666
MLS# 2121852Listed by: NICOSIA REALTY INC.
$30,000Active0.63 Acres126 Ramsey Drive, Melrose, FL 32666
MLS# 2121869Listed by: NICOSIA REALTY INC.